Dr D'Souza is a Professor of Medicine and the Associate Chief, Research in the Division of Hematology/Oncology at the Medical College of Wisconsin in Milwaukee and serves as Chair of the Plasma Cell Disorders group within the Froedtert & MCW Cancer Center. She conducts clinical and translational research in multiple myeloma and light chain amyloidosis with funding support from the National Institutes of Health and foundations such as the Advancing a Healthier Wisconsin with over 200 peer-reviewed publications in this area.