SUMMARY

Ph.D. with 10 years of experience in precision oncology and cancer biology. Conceptualized and created several services/tools to increase uptake of precision therapies including an EMR extension the entire workflow for molecular tumor board starting with case submission to analytics on usage. Skilled at creating both provider and patient facing educational content and supported clinical trial feasibility queries and workflow enhancements for increasing uptake of precision therapies. Highly experienced in conceptualizing and working with clinical decision support systems, EMRs, and precision oncology knowledgebases.

WORK EXPERIENCE

Sr. Director, Precision Medicine – OneOncology, Sep 2022-Present

• Manage the precision oncology service portfolio for 20+ community oncology practices
• Conceive and launch services to make precision medicine accessible
• Co-develop tools for point-of -care access to precision oncology initiatives
• Advise on the data monetization strategies and projects in precision medicine space
• Identify, lead and execute quality improvement projects across the OneOncology network

Staff Scientist, Sr. - Vanderbilt Ingram Cancer Center (VICC), Sep 2021-Sep 2022

• Manage workflow for molecular tumor board at VICC and a virtual international molecular tumorboard
• Work with oncologists, physician scientists and data scientists to query patient data for clinical trial feasibility analysis and other operational improvement projects
• Create micro-learning video content for oncologists, and fellows. Topics include data sources within and outside VUMC, accessing these data sources, data science tips, and career development
• Collaborate with oncologists at Baptist Memorial, Memphis, TN to identify areas/sites for introducing clinical decision support with the aim to increase clinical trial enrollment for under-served and minority populations
• Initiated and led a meditation study at VICC with the aim to study best practices to integrate meditation intervention as part of routine cancer care (on zero budget)

Staff Scientist - Vanderbilt Ingram Cancer Center (VICC), Sep 2017 - Sep 2021

• Led the ProMPT (Provider Messaging for Precision Therapies)—an initiative to increase uptake of targeted therapies as well as biomarker-driven trials at VICC
• Conceptualized and created the whole workflow for setting up molecular tumor board starting with case submission, case presentation, report formats, report generation, report upload to EMR, analytics on usage
• Conceptualized and created the whole workflow for Our Cancer Genomes—International virtual tumorboard that allows community oncologists to
• present their patients and gather expert advice from a multi-disciplinary panel
• Successfully lead the design, development, and UI testing of CMOCS (Clinical Molecular Oncology Consult Service), through multiple design cycles
• Led the precision clinical trial enrollment initiative at VICC
• Conceptualized and built clinical trial matching workflows for clinical trial pre-screening in different scenarios
• Performed manual curation and trained personnel for consortia such as AACR-GENIE and GE healthcare projects.

Research Analyst III- Vanderbilt Ingram Cancer Center (VICC), Sep 2016-Sep 2017

• Performed expert manual curation of ~1400 biomarker driven solid cancer and heme malignancy clinical trials
• Led the development of clinical trial curation tool and clinical trial matching service acting as the technology liaison with GenomOncology Inc., (Cleveland, OH)
• Created expert content on oncology and biomarkers for the My Cancer Genome website (https://www.mycancergenome.org/ )

Post-doctoral Research Fellow – Vanderbilt University Medical Center (VUMC), March 2015-June 2016

• Identified microRNA important in lung cancer metastasis and growth
• Created and optimized protocols for human cancer cell-lines
• Skilled at RT-PCR, DNA/RNA extraction, migration & invasion assays, growth assays, protein purification, and imaging.
• Designed experiments, generated publication quality figures, and presented results with critical analysis

Teaching Assistant – New Jersey Institute of Technology (NJIT), July 2011-Jan 2015

• Managed the initial startup and setup of a stem cell culture lab and created best practices documentation
• Trained and supervised undergraduate and graduate students on stem cell-culture techniques
• Created and maintained laboratory protocols and inventory for lab supplies
• Co-ordinated laboratory equipment setup for undergraduate lab-work
• Graded homework and communicated with students about their progress
• Assisted in preparing teaching material for undergraduate courses

Research Assistant – New Jersey Institute of Technology (NJIT), Jan 2010- July 2011

• Trained and supervised graduate students on neuronal cell-culture techniques
• Supported harvest of neuronal cells from rat tissue
• Created and maintained laboratory protocols and inventory for lab supplies
• Trained and supervised undergraduate and graduate students in the use of cell culture within 3D Polydimethylsiloxane (PDMS) devices 

Assistant Manager, Atul Ltd. India, July 2006-May 2008

• Successfully managed and executed projects on solvent loss detection and minimization
• Designed experiments to recover usable products from liquid chemical waste
• Collaborated with engineers, scientists, and management officials across multiple dept. for project execution

EDUCATION

• Ph.D., Biomedical Engineering, New Jersey Institute of Technology (NJIT) & Rutgers State University of New Jersey, Newark, NJ, Jan 2015

Dissertation: Developing an insulin producing tissue using mouse embryonic stem cells

• M.S. in Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ, May 2010

Thesis: Axon guided axon growth in DRG neurons from the spinal cord of rat embryos               

• B.E in Chemical Engineering, L.D. College of Engineering, Ahmedabad, Gujarat, India, July 2006

PEER-REVIEWED PUBLICATIONS

• Clinical Value of Timely Targeted Therapy for Patients With Advanced Non-Small Cell Lung Cancer With Actionable Driver Oncogenes, Oncologist, Feb 2024 (https://pubmed.ncbi.nlm.nih.gov/38417095/ )
• Jain, NM, Wang, LL, Anglemyer, A, Osterman, TJ, Self-Service to Concierge Data Delivery: One Cancer Center’s Story (Submitted to JCO-Oncology Practice, Under review, July 2022)
• Jain NM, Holt ME, Micheel CM, Levy MA. A Landscape Analysis of Breast Cancer and Acute Myeloid Leukemia Trials Using the My Cancer Genome Clinical Trial Data Model, JCO Clinical Cancer Informatics, 2021 :5, 975-984
• Holt ME; Mittendorf, KF; Lenoue-Newton, ML; Jain NM; Anderson, IA; Lovly, CM; Osterman, TJ; Micheel, CM; Levy, MA.  My Cancer Genome: Coevolution of Precision Oncology and a Molecular Oncology Knowledgebase, JCO Clinical Cancer Informatics 2021 :5, 995-1004
• Jain NM, Schmalz L, Cann C, Holland A, Osterman Travis, Lang K, Wiesner GL, Pal T, Lovly C, Stricker T, Micheel C, Balko JM, Johnson DB, Park BH, Iams W. Framework for Implementing and Tracking A Molecular Tumor Board at an NCI-Designated Comprehensive Cancer Center. Oncologist. 2021 Aug 14. doi: 10.1002/onco.13936. Epub ahead of print. PMID: 34390291.
• Jain, NM, Culley, A, Micheel, CM, Osterman TJ, Levy, MA. Learnings from Precision Clinical Trial Matching for Oncology Patients Who Received NGS Testing, JCO Clinical Cancer Informatics, 2021
• Jain, NM; Mittendorf, KF; Holt, ME; Lenoue-Newton, ML; Maurer, I; Miller, C; Stachowiak, M; Botyrius, M; Cole, J; Micheel, CM; Levy, MA. The My Cancer Genome clinical trial data model and trial curation workflow, Journal of the American Medical Informatics Association, Volume 27, Issue 7, Pages 1057–1066, July 2020
• X Ma, NM Jain, P Hitscherich, S Seetamaraju, EJ Lee, Stem cell derived insulin-producing cells in 3D engineered tissue in a perfusion flow bioreactor, Tissue Engineering, Nov 2020
• Jain, NM, Culley, A, Knoop T, Micheel, CM, Osterman TJ, Levy, MA. Conceptual Framework to Support Clinical Trial Optimization and End-to-End Enrollment Workflow, JCO Clinical Cancer Informatics, June 2019 (Accepted without revisions)
• Greenwalt EJ, Edmonds MD, Jain NM, Adams CM, Mitra R, Eischen CM. Targeting of SGK1 by miR-576-3p Inhibits Lung Adenocarcinoma Migration and Invasion. Molecular Cancer Research; Sep 2018
• Jain NM, Lee EJ. Islet endothelial cell-derived from mouse embryonic stem cells – Cell Transplantation, March 2015.

POSTERS

• Jain, NM, Lammers, PE, Savona, MR, Osterman, TJ, Goorha, S. Using a standard implementation science framework to improve clinical trial enrollment for a community Tennessee oncology center. Journal of Clinical Oncology 2022 40:16_suppl, e18586-e18586. ASCO 2022
• Jain, NM, Schremp, E, Spalluto, L, Osterman, TJ, Friedman, DL, Incorporating mediation-based interventions at an academic cancer center: A six-step process. Journal of Clinical Oncology 2022 40:16_suppl, e18662-e18662, ASCO 2022
• Rahman, Protiva & LeNoue-Newton, Michele & Chaugai, Sandip & Holt, Marilyn & Jain, Neha & Maxwell, Christina & Micheel, Christine & Yang, Yuanchu & Ye, Cheng & Schultz, Nikolaus & Riely, Gregory & McCarthy, Caroline & Rizvi, Hira & Schrag, Deborah & Kehl, Kenneth & Lepisto, Eva & Yu, Celeste & Bedard, Philippe & Fabbri, Daniel & Warner, Jeremy. (2021). Clinical and genomic predictors of brain metastases (BM) in non-small cell lung cancer (NSCLC): An AACR Project GENIE analysis. Journal of Clinical Oncology. 39. 2032-2032. 10.1200/JCO.2021.39.15_suppl.2032.
• Micheel, CM; LeNoue-Newton, ML; Holt, ME; Jain, NM; Levy, MA; Augmenting the My Cancer Genome knowledge resource with data from AACR Project GENIE, Cancer Research 80 (16 Supplement), 2020, 2058-2058
• Jain, NM, Micheel, CM, Park, BH. Provider notification for new oncology approvals for biomarker-driven therapies, CGC Conference, 2019 (Accepted for a platform presentation)
• Jain, NM, Micheel, CM, Park, BH. Molecular tumor board efforts at Vanderbilt-Ingram Cancer Center, Poster at CGC conference, 2019
• Holt, M.E., Micheel, C.M., Anderson, IA, Lenoue-Newton, ML, Jain, NM, Miller, C, Botyrius, M, Maurer, I, Yeakley, J, Vannelli, L, Levy, MA. MCG 2.0: A highly curated, scalable precision cancer medicine resource. CGC Conference, 2019 (Accepted for a platform presentation)
• Jain, NM, Culley, A, Osterman, TJ, Levy, MA. Learnings from a pragmatic study to evaluate benefit of performing reflex clinical trial matching and providing clinical decision support to physicians; ASCO 2019
• Jain NM, LeNoue-Newton ML, Anderson IA, Micheel CM, Levy MA. Assessment of breast cancer trial landscape utilizing a structured clinical trial knowledgebase; Cancer Genetics 226, 54; 2018. (Won 1^st prize for poster presentation)
• Anderson IA, Jain NM, LeNoue-Newton ML, Micheel CM, Levy MA. Data and knowledge sharing to improve patient care: The VICC and MCG experience; Cancer Genetics 226, 38-39; 2018 (Accepted for a platform presentation)
• LeNoue-Newton ML, Jain NM, Anderson IA, Micheel CM, Levy MA. Biomarker driven clinical trial curation and search; Cancer Genetics 226, 46; 2018 (Accepted for a platform presentation)
• Jain NM, Mittendorf KF, Micheel CM, Levy MA. Assessment of actionability of cancer genomic testing panels based on a structured clinical trial knowledge base; ASCO 2017 (Abstract accepted for poster presentation)
• Osterman TJ, Jain NM, Mittendorf KF, Micheel CM, Levy MA. Utility of adding clinical data to a molecular results portal for improving clinical trial prescreening efficiency; ASCO 2017
• Jain NM, Lee EJ. Islet endothelial cell-derived from mouse embryonic stem cells. Presented at: New York Stem cell conference; 2013 Oct 16-17; New York City, New York
• Jain NM, Haq-Siddiqi N, Lee EJ. A 3D microfluidic gel system for stem cell derived endothelial cells. Presented at: Bio Medical Engineering Society Annual Meeting; 2013NewYork Stem cell conference; 2013 Sep 25-28; Seattle, Washington
• Jain NM, Lee Eun Jung. Endothelial cells as a side product from mouse embryonic stem cell differentiation into pancreatic islet cells. Presented at: Cellular and Molecular bioengineering conference; 2013 Jan 1-5, Waimea, Hawaii
• Jain NM, Pfister BJ, Perez-Castillejos R. Microfluidic devices to study the interaction between endothelial cells and neurons. Paper presented at: Faraday Discussion 146- Graduate Research Seminar; 2010 April 9-14; Richmond, Virginia
• Jain NM, Pfister BJ, Perez-Castillejos R. Microfluidic devices to study the interaction between endothelial cells and neurons. Presented at:  2010 Metro Area Micro Electro-Mechanical Systems/Nano Electromechanical Systems Workshop; 2010, July 26; Hoboken, New Jersey
• Jain NM, Pfister BJ, Perez-Castillejos R. PDMS devices for studying Dorsal Root ganglia (DRG). Presented at: 2010 Bio Medical Engineering Society Annual Meeting; 2010, October 6-10; Austin, Texas

RESEARCH EXPERIENCE

• Post-doctoral Research Fellow – Vanderbilt University Medical Center (March 2015-June 2016)
  • Identified microRNA important in lung cancer metastasis and growth
  • Created and optimized protocols for human cancer cell-lines
  • Skilled at RT-PCR, DNA/RNA extraction, migration & invasion assays, growth assays, protein purification, and imaging.
  • Designed experiments, generated publication quality figures, and presented results with critical analysis
• PhD Candidate – New Jersey Institute of Technology (NJIT) & Rutgers State University of New Jersey                            (Jan 2010- Jan 2015)        
  • Successfully created a novel 3D tissue—using beta cells and islet endothelial cells derived from mouse embryonic stem cells embedded in a collagen matrix using a perfusion-flow bioreactor
  • Was instrumental in setting up a stem-cell laboratory (I was my professor’s first graduate student)
  • Trained incoming graduate and undergraduate students in cell culture and microscopy techniques
  • Created and optimized protocols for stem cell cultures, western blotting, PCR, ELISA, and other techniques

VOLUNTEER WORK

Certified Meditation & Yoga Instructor, Art of Living Foundation, July 2010-Present

• Conduct SKY breath and meditation workshop for teens, students and young professionals
• Conduct various meditation, breathwork and stress management workshops for individuals and groups in TN, KY, AL, and NC area.

Events Coordinator, Art of Living Foundation, Jan 2014-Present

• National event coordinator for meditation retreats (attended by >4000 participants globally)
• Managed teams of 200+ volunteers from around the US for large meditation retreats at the Art of Living Retreat Center, Boone, NC

COMMUNITY LEADERSHIP EXPERIENCE

• Invited speaker and breathwork coach at Healthstream (Nashville, TN), Deloitte (Hermitage, TN)
• Invited to St. Thomas Outpatient clinic (Franklin, TN) for teaching breathwork and meditation to stroke patients

FELLOWSHIPS AND AWARDS

• National Science Foundation (NSF) Fellowship, May 2010
• Graduate Research Assistantship, July 2011
• Best Poster Award (1^st Prize, Cancer Genomics Consortium, Nashville, TN), Aug 2018