Annette von Drygalski is a Professor of Clinical Medicine in the Division of Hematology/Oncology, and Director of the Hemophilia and Thrombosis Treatment Center, Department of Medicine, at the University of California, San Diego.

Dr. von Drygalski earned her pharmaceutical and medical degrees from the Ludwig Maximilians University, Munich, Germany. She completed residency in Internal Medicine at the Medical College of Wisconsin, Milwaukee, and fellowship in Hematology and Oncology at the University of California, San Diego and The Scripps Research Institute.

Dr. von Drygalski is dedicated to the care of patients with hemophilia and other bleeding disorders addressing the evolving needs of aging patients with hemophilia, such as new therapies, cardiovascular disease and hypertension as well as the progression of hemophilic joint disease. In this role, Prof. von Drygalski investigates novel molecules and gene therapy in clinical trials, and elucidates effects of new treatments on the pathobiology of joint health, both at the bench and in translational studies.

von Drygalski has pioneered musculoskeletal ultrasound for rapid joint bleed detection and joint evaluation in hemophilia. She is certified in musculoskeletal ultrasound by the American Registry for Diagnostic Medical Sonography, and has developed the Joint Activity and Damage Exam (JADE), a validated ultrasound protocol to quantify synovial and osteochondral changes as well as inflammation in the hemophilic joint. She is also the Director of the CME-accredited course “Musculoskeletal Ultrasound in Hemophilia” at the University of California San Diego.

Dr. von Drygalski has also developed a focus in international outreach to afford training for hematologists from developing countries and establish care for patients with hemophilia and bleeding disorders in Mozambique. In that realm she is investigating anemia and the post-partum hemorrhage, raising awareness to establish multi-disciplinary collaborations to mitigate mortality.