4th Binaytara Precision Oncology Summit: Current Standards and Emerging Therapies

San Francisco, CA US
October 5, 2024 to October 6, 2024

The 4th Binaytara Precision Oncology Summit is a 2-day CME-accredited conference that offers an unparalleled opportunity for oncology professionals to delve into the latest advancements, innovations, and practices in precision oncology. The theme for this year's summit, "Current Standards and Emerging Therapies," highlights the conference's commitment to providing a comprehensive overview of the field, including in-depth discussions on the latest developments in precision oncology, alongside a thorough examination of established treatment protocols. Focus on actionable mutations ensures that the presented information translates directly into improved patient care.

The summit features didactics, panel discussions, interactive case studies, and scientific abstract presentations. 

This conference will augment healthcare providers' foundation of knowledge and clinical competence in several areas, including:

  • Integrating different platforms available for testing actionable molecular alterations to identify targeted therapy options.
  • Current and evolving paradigms in precision oncology approach for management of common malignancies.
  • Trends, challenges, controversies, and cost-considerations of precision oncology approaches and targeted therapies.

Target Audience

  • Hematologists/Oncologists
  • Oncology Nurse Practitioners
  • Oncology Pharmacists
  • Oncology Physician Assistants
  • Oncology Fellows/Residents
  • Oncology Nurses
  • Researchers and others involved in the care of cancer patients

Organizing Committee 

Program Director:

Dr. Binay Shah - Binaytara Foundation

Organizing Committee:

Dr. Mark Pegram - Stanford University

Dr. Siddhartha Yadav - Mayo Clinic

Abstract Committee Chair

Dr. Jonathan Wesley Riess, MD, MS - UC Davis

Learning Objectives

Upon successful completion of this educational activity on precision oncology, participants will be able to:

  • Identify frequent molecular abnormalities across several common malignancies and understand the appropriate timing of testing to detect these abnormalities.
  • Interpret results of next-generation sequencing and other biomarkers predictive of response to targeted therapies and recognize the challenges involved.
  • Explain the role, including advantages and disadvantages, of different testing methodologies available for a selection of targeted therapies.
  • Plan optimal molecular-targeted treatment strategies for the treatment of cancer.
  • Outline emerging research, the mechanism of action, and the role of novel molecular-targeted therapies in a clinical investigation for cancer patients.
Course summary
Course opens: 
Course expires: 
Event starts: 
10/05/2024 - 8:00am PDT
Event ends: 
10/06/2024 - 3:30pm PDT

DAY 1 - OCTOBER 5th, 2024


07:00 AM – 07:45 AM: Registration and Exhibits

07:45 AM – 07:50 AM: Welcome

07:50 AM – 08:00 AM: Binaytara Foundation's Efforts in Improving Cancer Care Disparities

08:00 AM – 09:00 AM: Session 1: Beyond NGS: Tools in Precision Oncology

Session Chair:

08:00 AM – 08:15 AM: WGS, WES, and Mutational Signatures for identification of complex genomic alterations driving cancer development and progression

08:15 AM – 08:30 AM: Potential clinical application(s) of transcriptomics and proteomics

08:30 AM – 08:45 AM: CTCs and ctDNA to aid therapeutic decisions and surveillance

08:45 AM – 09:00 AM: Discussion

09:00 AM – 10:00 AM: Session 2: DNA-repair deficiencies and genomic instability

Session Chair: James M. Ford, MD, FASCO

09:00 AM – 09:15 AM: Biomarkers of DNA-repair deficiencies, HRD, and genomic instability

09:15 AM – 09:30 AM: Current treatment landscape for HR deficient and genomically unstable tumors

09:30 AM – 09:45 AM: Next generation of DNA-repair deficiency targeted treatments

09:45 AM – 10:00 AM: Discussion

 10:00 AM – 10:30 AM: Break and Exhibits

10:30 AM – 11:45 AM: Session 3: Cancer immunotherapy

Session Chair: Diwakar Davar, MD

10:30 AM – 10:45 AM: Targeting tumor microenvironment and immune evasion pathways

10:45 AM – 11:00 AM: Innate immune signaling pathways: How to turn ‘cold’ tumors into ‘hot’ ones?

11:00 AM – 11:15 AM: Predicting response/resistance to immune checkpoint inhibitors

11:15 AM – 11:30 AM: Engineering immune cells to treat cancer (CAR-Ts and beyond)

11:30 AM – 11:45 AM: Discussion

11:45 AM – 01:00 PM: Lunch and Exhibits

01:00 PM – 01:45 PM: Session 4: Keynote

01:00 PM – 01:30 PM: Keynote lecture

01:30 PM – 01:45 PM: Discussion

01:45 PM – 02:45 PM: Session 5: RAS/RAF/MAPK and PI3kinase/AKT/mTOR Signalling

Session Chair:

01:45 PM – 02:00 PM: Therapeutic opportunities leveraging aberrant RAS/RAF/MAPK signaling

02:00 PM – 02:15 PM: Therapeutic opportunities leveraging aberrant PI3 kinase/AKT/mTOR signaling - Neil M. Iyengar, MD

02:15 PM – 02:30 PM: Resistance mechanisms and challenges to targeting RAS/RAF/MAPK and PI3 kinase/AKT/mTOR pathways

02:30 PM – 02:45 PM: Discussion

02:45 PM – 04:00 PM: Session 6: Targeting receptor tyrosine kinases

Session Chair: Jonathan Wesley Riess, MD, MS

02:45 PM – 03:00 PM: Introduction to the receptor tyrosine kinase in cancer development and progression across tumor types

03:00 PM – 03:15 PM: A primer on tyrosine kinase inhibitors and implications for management of EGFR, HER2, ROS1, RET, ALK, MET and NTRK altered tumors

03:15 PM – 03:30 PM: HER2 signaling in breast and other cancers, and implications for treatment - Mark Pegram, MD

03:30 PM – 03:45 PM: Overcoming challenges in targeting receptor tyrosine kinases and resistance mechanisms

03:45 PM – 04:00 PM: Discussion

04:00 PM – 06:00 PM: Session 7: Oral abstracts with networking

Session Chair: Jonathan Wesley Riess, MD, MS


DAY 2 - OCTOBER 6th, 2024


07:00 AM – 08:30 AM: Session 8: Poster abstracts and breakfast

Session Chair: Jonathan Wesley Riess, MD, MS

08:30 AM – 09:30 AM: Session 9: Hormone receptor signaling

Session Chair:

08:30 AM – 08:45 AM: Advances in estrogen receptor signaling and biology

08:45 AM – 09:00 AM: Therapeutic options for ESR1-mutant breast cancers - Aditya Bardia, MD, MPH, FASCO

09:00 AM – 09:15 AM: Treatment strategies targeting the androgen receptor

09:15 AM – 09:30 AM: Discussion

09:30 AM – 10:45 AM: Session 10: Molecular tumor board

Session Chair: Siddhartha Yadav, MBBS, MD

09:30 AM – 09:45 AM: Case 1 and discussion

09:45 AM – 10:00 AM: Case 2 and discussion

10:00 AM – 10:15 AM: Case 3 and discussion

10:15 AM – 10:30 AM: Case 4 and discussion

10:30 AM – 10:45 AM: Case 5 and discussion

10:45 AM – 11:00 AM: Break and Exhibits

11:00 AM – 12:00 PM: Session 11: Cancer interception and prevention

Session Chair:

11:00 AM – 11:15 AM: Multi-cancer early detection tests – clinical utility and pitfalls

11:15 AM – 11:30 AM: Personalized vaccines for primary or secondary cancer prevention

11:30 AM – 11:45 AM: Precision in cancer risk prediction incorporating genetic, hormonal, and environmental risk factors: Implications for cancer prevention

11:45 AM – 12:00 PM: Discussion

12:00 PM – 01:00 PM: Lunch and Exhibits

01:00 PM – 02:00 PM: Session 12: Precision oncology drug development (Part 1)

Session Chair: Shivaani Kummar, MD, FACP

01:00 PM – 01:05 PM: Precision oncology drug development - Shivaani Kummar, MD, FACP

01:05 PM – 01:20 PM: Identifying predictive markers of response and resistance in cancer therapeutics

01:20 PM – 01:35 PM: Role of AI in oncology drug development

01:35 PM – 01:50 PM: How to design precision clinical trials for the rare targets

01:50 PM – 02:00 PM: Discussion

02:00 PM – 03:00 PM: Session 13: Precision oncology drug development (Part 2)

Session Chair: 

02:00 PM – 02:15 PM: Antibody-drug conjugates: opportunities and challenges

02:15 PM – 02:30 PM: Monoclonal and Bispecific antibodies: where do we stand now?

02:30 PM – 02:45 PM: Small molecules for precision oncology: opportunities and challenges

02:45 PM – 03:00 PM: Gene-based therapy – is the future here?

03:00 PM – 03:15 PM: Discussion

03:15 PM – 03:30 PM: Closing remarks

Hyatt Regency San Francisco Downtown Soma
50 3rd St
San Francisco, CA 94103
United States


All conflict of interest has been identified and mitigated for individuals in control of contents.


None of the members of the planning committee, nor any member of their immediate families, have a relevant financial interest in or affiliation with any commercial supporter of this educational activity and/or with the manufacturer(s) of commercial products and/or providers of any commercial services discussed in this educational activity.

If you are interested in exhibiting at this meeting, please visit our exhibit page here - https://education.binayfoundation.org/exhibit-information



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All marketing and product promotion activities must occur in the designated exhibit hall or product theater space separate from the area where this accredited continuing education takes place. 

The exhibit and product promotion space is reserved only for companies that have purchased marketing and product promotion slots at the conference.  The individual registration fee doesn't include marketing or product theater privileges. Please refer to the sponsorship handbook for the types of marketing activities included in your display/sponsorship fees. 

If your company has NOT purchased a marketing opportunity such as an exhibit table, product theater slot or another type of marketing opportunity, you may not participate in any marketing activity or attempt to educate healthcare providers about your product or service. Industry attendees of companies without marketing opportunities must refrain from interacting with healthcare providers at this meeting in any form, including introducing themselves as an employee of the company, discussing the care of patients, handing out flyers and brochures, inviting participants to the company's other programs, etc.

Violating this policy will result in a fine equivalent to a general display fee for that conference. 



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  • If your company has NOT purchased a display table at the event AND you attended the meeting paying a full industry registration fee, BUT YOU PARTICIPATED IN MARKETING AND PROMOTIONAL ACTIVITIES, you will be billed a full GENERAL DISPLAY FEE for that event. 

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You may cancel your enrollment at any time. Cancellation fees apply as below:

  • 50% of the paid registration fee will be refunded if registration is canceled six weeks before the conference.
  • No refunds will be issued if registration is canceled after that date.  

No credits will be offered if you do not complete all required steps of this activity, including registration and participation in the live meeting.